Ferrara,Italy: Approximately 25% of female infertility cases are unexplained, which causes women to have a very few options other than expensive fertility treatments. Alcohol, caffeine and bad diet have all been linked to poor fertility, but up until now no one has blamed the humble kiss. But now, a team at the University of Ferrara in Italy says kisses may be the reason for unexplained infertility in women. A not-so-known herpes virus can be transmitted through the saliva, and can make women infertile. They examined the uteruses of women with unexplained primary infertility - the inability ever to bear a child - and found that 43 per cent of them were infected byHHV-6A, one of the human herpes viruses. The virus was not found in any of the women whose fertility was normal. Infertility affects approximately 6 per cent of women aged from 15 to 44. The virus is typically not detectable in the blood or saliva, so its true prevalence is unknown. However it replicates in the salivary glands and previous research indicates it can be transferred through kissing. "Indeed, there are several potential mechanisms by which HHV-6 might induce female infertility. Viral infections might trigger eNK cell functional modifications that could also induce aberrant expression of cytokines thereby promoting a dysfunctional uterine environment,” said the study’s senior author, Roberta Rizzo. Published in the journal Plos One, the study describes how all the women infected with HHV-6A were found to have abnormal levels of cytokines, which are signalling proteins that facilitate interactions between cells that play an important role in supporting fertilised eggs and foetal development. The team says more research is now needed to confirm the findings, which came from a cohort of 66 women, and to determine whether antiviral treatment would help women with the uterine infection. The scientists also found higher levels of the hormone estradiol, which fluctuates with the menstrual cycle and may trigger the HHV-6A infection. “This is a surprising discovery,” said Anthony Komaroff, a professor at Harvard Medical School who has studied HHV-6. “If confirmed, the finding has the potential to improve the outcome for a large subset of infertile women.”
Washington: Pregnancy might seem like the perfect time to sit back and relax. You likely feel more tired than usual, and your back might ache from carrying extra weight. But unless you're experiencing complications, sitting around won't help. In fact, pregnancy can be a great time to get active — even if you haven't exercised in a while. According to American College of Obstetricians and Gynecologists (ACOG) too, one can safely take part in 30 minutes or more of moderate exercise every day, as long as she don't have a medical condition or complication. Because, exercising during pregnancy shields a woman from backaches, constipation, bloating and swelling. It also boost the mood and hikes energy level. Moreover, it helps to get a better sleep and the resulted mental health. Gaining weight and losing their body features during and after pregnancy worries all women and exercising is the best remedy. It also promotes muscle tone, strength and endurance which in turn make the delivery easy. Exercise during pregnancy might also reduce the risk of gestational diabetes. Walking is a great exercise for beginners as it provides moderate aerobic conditioning with minimal stress on joints. Other good choices include swimming, low-impact aerobics and cycling on a stationary bike. Strength training too is appreciable, as long as you stick to relatively low weights. Overall, general exercise stretches and strengthens the muscles, to cope up with the aches and pains of pregnancy. Stretches ease back pain, walking improves blood circulation and swimming can strengthen the abdominal muscles. Intense exercise increases oxygen and blood flow to the muscles and away from your uterus. In general, you should be able to carry on a conversation while you're exercising. If you can't speak normally while you're working out, you're probably pushing yourself too hard and such intense exercising may result in pre term delivery. Remember to warm up, stretch and cool down. Drink plenty of fluids to stay hydrated, and be careful to avoid overheating. Giving birth is akin to running a marathon, which requires stamina, determination and focus. So, training for childbirth through exercise may ease labour and even shorter the time it takes to deliver the baby.
Jessica Mah founded inDinero, a small business services start-up, when she was just 19 years-old and received $1 million in funding by the time she was 20.The tech wiz began programming at 8 years-old, started her first company at 12 and dropped out of high school to take computer science courses at University of California at Berkeley when she was 15. In 2010, TechCrunch wrote that she was, “Perhaps the closest we’ve got to a female Mark Zuckerberg.” After just one year, her company was on the brink of failure. She was burning through $80,000 a week and couldn’t get along with any of her co-workers. “I overspent, I overhired, I wasn’t focused on generating enough revenue to sustain the business,” says Mah. InDinero was initially billed as a “Mint.com for small business owners,” but she found that her 30,000 customers didn’t feel like the product was worth paying for and only used free services. The company ran through its funding quickly and by the time they were down to their last $150,000 Mah realized she had to make drastic changes. “I feel like I’m Bernie Madoff–rich on the outside, but completely broken on the inside,”. She laid off all but two of her eight employees and moved the company out of its office and into her apartment. “We regrouped,” says Mah. “And we came up with the idea to do inDinero full-service. So instead of just being software we decided to charge thousands of dollars more but also handle all of the accounting and tax needs for a business.” The rebranding worked—inDinero has grown 2,686% in the past three years and now has four offices around the globe. “We went from eight employees to no employees near death, near bankruptcy and now we have about 130 full-time team members working at inDinero,” says Mah. Last year Mah and cofounder Andy Su, 24 decided to go to marriage therapy to improve their business partnership. The couple has never been in a romantic relationship. “Business partners have conflict sometimes,” she explains. “We yell at each other but we love each other too. Marriage counseling has really helped us figure out how to be better partners for each other.” It’s been a long journey – and it’s only just begun. Mah is just 25 years-old and plans to continue expanding inDinero. This month she was featured on the cover of Inc. Mag’s 5000 issue, which features the fastest-growing private US companies.